Why Russia was unable to launch its own vaccine into mass production

The epidemiological situation in Russia and around the world remains rather difficult. At the same time, domestic pharmacologists have already been able to create three vaccines against COVID-19. Does this mean that very soon vaccinations will be able to defeat the coronavirus, and our country will earn from the export of a billion doses of vaccine? Alas, everything is a little more complicated than we would like.

Officials at the highest level declare the start of mass vaccination of Russians by the end of 2020. The choice is quite wide: there are three vaccines on the way from the Vector Research Center, the Gamaleya Center and the Chumakov Center of the Russian Academy of Sciences. As it turned out, when developing them, all medical institutions went their own way.

The fact is that vaccines against the virus can be created in many ways. As you know, the first in the world to receive the Sputnik V vaccine was announced by the N.F. Gamalei. A drug was created based on an adenovirus, in which part of its genome was replaced with the genome of the coronavirus. According to the developer, the effectiveness of the drug is 92%. True, so far there are tests on volunteers and it is too early to seriously believe in the reliability of the vaccine. It is also unknown how long the post-vaccination effect will be. In general, this center acted rather atypically, registering the drug before the end of the third phase of the trial. The PR effect was strong, it is to be hoped that the real efficiency will not disappoint in the end.

The Chumakov Center follows the same path as its Chinese colleagues, working with the so-called inactivated, or "killed" coronavirus. This method is considered the safest because it cannot cause disease. So, for example, a vaccine against tick-borne encephalitis was once created. Center "Vector" tried six methods at once, of which only one in fact turned out to be non-toxic and effective. As a result, the peptide preparation "EpiVacCorona" was obtained, which is now undergoing mass tests. Western pharmaceutical corporations Pfizer and BioNTech also go their own way, which is considered the most modern. To develop immunity in the body, they use small fragments of informational ribonucleic acid. As experts point out, the Americans are ahead, but "groping", since there is no established practice for this method so far.

It would seem that we have as many as three of our own vaccines on the way, it remains to vaccinate the population and make money on the sale of the promised billion doses abroad. But all these Napoleonic plans stumble over the lack of sufficient production capacity in our country. The first "bell" sounded when it was announced that Russia would not export the vaccine itself, but only technology its production. Making a small trial batch of the drug is not a problem. Scaling up production becomes a problem.

At first, even with many large bioreactors, scaling up production on them can take at least a year. This is a complex biotechnological process that requires individual calibration. At the slightest violation of technology, the resulting vaccine is rejected. Debugging is possible only through experience, which takes a lot of time.

Secondly, Russia simply does not have enough of these largest bioreactors, which President Putin himself was recently forced to admit at the highest level:

There are certain problems associated with the presence or absence of a certain amount of equipment - "hardware", as they say - for the deployment of mass production.

Recently, the press leaked information that Moscow asked Paris for technological assistance with the production of the Sputnik V coronavirus vaccine. The French business publication Challenges commented:

The Russians have been asking us for weeks if we want to work with them. In reality, this shows their main weakness - they have no production capacity.

As reported, so far President Macron has not gone to meet the Kremlin, citing the need to consult with his scientific luminaries. A good reason to once again think about Russia's dependence on the supply of imported equipment, isn't it? It is possible that while we have established mass production of a vaccine against coronavirus, most of the country's population will be happily ill with it. Probably, first of all, it is worth taking care of helping the weakest, the elderly and those suffering from serious illnesses, who are at risk.
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  1. amateur Offline amateur
    amateur (Victor) 28 November 2020 14: 44
    Information from the OBS news agency (one woman said). Retelling gossip even without specifying sources!
    ps Mr. Marzhetsky will now once again write to me that I cannot read. drinks
    1. Marzhecki Offline Marzhecki
      Marzhecki (Sergei) 29 November 2020 08: 33
      Quote: layman
      ps Mr. Marzhetsky will now once again write to me that I cannot read.

      You don't know how to think smile And the sources are indicated, but you read selectively.
      1. amateur Offline amateur
        amateur (Victor) 29 November 2020 09: 40
        And the sources are indicated, but you read selectively.

        Recently information leaked to the press

        Mr. Marzhetsky! The word "press" is a collective word, therefore it cannot be referred to. The source can be an interview, article, etc. As a journalist, you should know this. And I read carefully. Well, thinking about is your problem. It is you who write the articles.

        The whole day is a continuous work of the mind.
        On the forehead - impassable thought:
        to whom to arrange a godfather for him,
        to whom to adapt godfather?

    2. Sidor sidorini Offline Sidor sidorini
      Sidor sidorini (Sidor) 7 December 2020 09: 05
      You can criticize any given, but the fact is obvious - the Russian economy shines with its extreme inefficiency. And this is a fact! What industry practically do not take everywhere a blockage.
      And the fact that the president is unable or unable to change the situation in the economy is a clinical fact.
      Education, health care, culture, science are all key for the state in the corral and eternal reform. When to work for the result, if reforms and experiments on living things continue.
      And the "best" entrepreneurs of Russia, a hundred of them, or it doesn't matter anymore, will not help, not managers are needed, but strategists, and as they were not in power, they are not. There are only momentary scale solvers.
  2. steelmaker Offline steelmaker
    steelmaker 28 November 2020 18: 45
    Why Russia was unable to launch its own vaccine into mass production

    Because you have to build and create. And our government can only sell and betray!
    1. orange Offline orange
      orange (ororpore) 28 November 2020 19: 07
      With the connivance of Putin, in the middle of the XNUMXs, residential complexes and shopping centers were built on the site of factories. Now this person "headed" the type of "industrialization" of Russia, about which all sorts of "done with us" trumpets. Industrialization in Russia is going on a snail's crawl.
    2. polev66 Offline polev66
      polev66 (Alexander) 29 November 2020 22: 13
      give a fairy tale about 80000 destroyed factories. how you zadolbali with your delirium. build what is in demand. Well, they will set up the factories and what will be produced there, and where, the main sales will be found? or that, as in a union with subsidies and at the expense of the people, then to maintain these factories and products to impose at the state level. passed already.
      1. Sidor sidorini Offline Sidor sidorini
        Sidor sidorini (Sidor) 7 December 2020 08: 52
        This is the point. There is no sane economic policy. And all from the fact that the president's liberal views are dominant, and his alleged state policy is aimed only at supporting the state apparatus as such. The rest is left to the mercy of the market, which is known to be relative.
  3. 89210393092 Offline 89210393092
    89210393092 (Igor) 28 November 2020 18: 58
    You're lying, Seryoga, like a BBC!

    1. steelmaker Offline steelmaker
      steelmaker 28 November 2020 19: 21
      The volume of production of a vaccine against coronavirus in Russia may reach 1,5 million doses in December, 3-3,5 million in January and then multiply - up to 15 million a month in the spring of next year, the head of the Ministry of Industry and Trade of the Russian Federation Denis Manturov told reporters.


      And do you think this is mass production? "And will our country earn by exporting a billion doses of vaccine?" In 10 years?
    2. Marzhecki Offline Marzhecki
      Marzhecki (Sergei) 29 November 2020 08: 33
      And when we managed to switch to you, I didn't understand? This is the first thing.
      And secondly, you can declare anything you want, the main thing is to really do it. Mr. Manturov did not specify how he intends to increase these volumes? Looking forward to supplying imported equipment? And if they do not deliver, then what? Will the plans be slightly adjusted?
      1. Boa kaa Offline Boa kaa
        Boa kaa (Alexander) 29 November 2020 12: 39
        Quote: Marzhetsky
        the main thing is to really do it.

        Yes, they seem to be doing it. But I would like, of course, faster and more.

        A new workshop for the production of pharmaceutical substances for the treatment of tuberculosis, hepatitis, HIV and COVID-19 has been opened at the Bratskhimsynthez enterprise of the Pharmasintez company. From 2021, the production of a substance for the production of drugs against oncological diseases will begin.
        BratskKhimSintez has the technological capabilities to produce 36 international generic names of pharmaceutical substances from the List of Strategically Important Medicines, and in the near future it is planned to expand the range to 40 INN.

  4. The comment was deleted.
  5. SASS Offline SASS
    SASS (sass) 28 November 2020 19: 00
    Quote: steel maker
    Why Russia was unable to launch its own vaccine into mass production

    Because you have to build and create. And our government can only sell and betray!

    Yeah ...)))
  6. orange Offline orange
    orange (ororpore) 28 November 2020 19: 03
    But we have an abundance of ventilators that burn and explode!
    1. Boa kaa Offline Boa kaa
      Boa kaa (Alexander) 29 November 2020 12: 43
      Quote: orange
      But we have an abundance of ventilators that burn and explode!

      Follow the requirements of the Safety Instructions: do not climb to wipe them with oily rags - and you will be happy! yes
    2. free_flier Offline free_flier
      free_flier 29 November 2020 17: 46
      Wake up.
      Your fan blows air into your face.
  7. Alexzn Offline Alexzn
    Alexzn (Alexander) 29 November 2020 10: 12
    Let's evaluate vaccines by their existence and use. Today, Russian vaccines are undergoing POST-REGMSTRATION (ha-ha) checks. As a result, we have a dozen vaccines around the world at approximately the same level of readiness, two of them actually have an impact on world exchanges and they are not Russian. It seems that Sputnik will not become the savior of humanity, as many Russians wanted, but, apparently, it will still be significant in world vaccination beyond the golden billion.
    1. free_flier Offline free_flier
      free_flier 29 November 2020 17: 48
      There are only almost 7 billion people outside the "golden" ...
    2. DimerVladimer Offline DimerVladimer
      DimerVladimer (Dmitry Vladimirovich) 30 November 2020 11: 22
      Quote: AlexZN
      Sputnik won't be the savior of humanity

      Satellite V did not take off ...

      In the USSR, they did it first - then they promoted it.
      In the Russian Federation, they first PR, then shrug ...

      This is not a mockery - I was counting on the vaccine, I have old parents, whom I regularly bring food and help.
      A third of relatives have already had covid disease.
      God forbid you bring your parents ...
      Sell ​​the vaccine!
  8. nikola bb Offline nikola bb
    nikola bb (nikolaj wasiljew) 29 November 2020 10: 20
    The lack of capacity for industrial production in this case only confirms the truth about the DE-INDUSTRIALIZATION of Russia in the post-Soviet period! As a result of this, a tragic gap arose between the achievements of science and the lack of means of implementing these achievements in practical life. And this applies to very many aspects of the economy. We vitally need not just "innovations" and "digitalization", but the RE-INDUSTRIALIZATION of the country!
    1. kapitan92 Offline kapitan92
      kapitan92 (Vyacheslav) 29 November 2020 14: 32
      We vitally need not just "innovations" and "digitalization", but the RE-INDUSTRIALIZATION of the country!

      You're right! Only, representatives of our "elite" do not "see" this need.
      The article is written on the merits of the issue. Manturov, when reporting to the Guarantor, after the registration of "Sputnik" in the Russian Federation, boldly promised about 30 million doses by the end of December this year. Then it turned out that there was no capacity. It is more expensive to repurpose existing capacities; specific types of medicines will disappear from the market. It is very costly to build new factories, technological lines, reagents and related materials are imported, and they have improved in price due to the rush demand.
      May God give it to "unwind" by mid-2021
      What can be demanded from our rulers if Russia still buys about 90% of insulin abroad? hi
    2. Yuri Kharitonov Offline Yuri Kharitonov
      Yuri Kharitonov (Yuri Kharitonov) 29 November 2020 18: 55
      And who should do it? It looks like Putin, there is no one else. And who steals when a state order for a grandiose construction appears, also Putin. And the rest of the citizens are simply out of business. Yes Yes exactly..

    3. 123 Offline 123
      123 (123) 29 November 2020 20: 16
      The lack of capacity for industrial production in this case only confirms the truth about DE-INDUSTRIALIZATION

      Excuse my curiosity, but which country has these same capacities in excess? Who had the factories at the ready? Well, what would be with what to compare ...
  9. Don36 Offline Don36
    Don36 (Don36) 29 November 2020 16: 55
    Here is a clear example of the fact that the people who promoted the post-industrial model of the economy for the Russian Federation are frankly not smart, if not saboteurs in the service of foreign states !!!
  10. Elena Ushkova Offline Elena Ushkova
    Elena Ushkova (Elena Ushkova) 29 November 2020 18: 39
    Author Sergei Marzhetsky was awarded a diploma by State Duma deputy Marchenko (ER) for "good news about Russia." She laughed. Why this particular deputy and where is the good news, Sergei?
  11. lahudra Offline lahudra
    lahudra (Nikolay Kondrashkin) 29 November 2020 21: 04
    Only the United States and France are able to organize the mass production of new vaccines, partly to the Netherlands, maybe Korea. Culture reactors and GMP sterility are very expensive.
  12. Jacques sekavar Offline Jacques sekavar
    Jacques sekavar (Jacques Sekavar) 29 November 2020 23: 37
    Provocative article.
    1. Mass production of vaccines in the Russian Federation has been established at three factories, and maybe even more.
    2. The newest biomaterials plant was launched in Bratsk
    3. The effectiveness of Russian vaccines does not raise doubts among specialists from different countries, except for those of the hackers of the foreign propaganda industry.
    4. Any product costs money and invites everyone to set up their own production of Russian vaccines.
    5. A pandemic is a global problem and therefore there is nothing wrong with cooperation and mutual assistance of different countries in the fight against this coronavirus.
  13. Kuznetsov Offline Kuznetsov
    Kuznetsov (Kuznetsov Alexander) 30 November 2020 13: 44
    It is true that the creation of vaccines and their mass production are different tasks.
    But in fact, there are only 4 countries in the world that can quickly create a vaccine and one of these countries is Russia, which is already very good. Moreover, they have created very effective vaccines. Misinformation stories of various kinds cannot undo this fact. People who understand at least something in this see it immediately.
    Nobody has yet launched the mass production of vaccines, and when it will be launched and who is unknown.
    The task of the state is to provoke its citizens and citizens of neighboring countries, and of those who buy the vaccine.
    And apparently yes, we need to create guaranteed production capacity of a universal nature for a couple of pandemics of this level, for yourself and that guy. That is, about 400 million doses per year. And quickly, in order to respond to the current pandemic.
    And universal capacity so that other microbiological preparations can be produced, not just vaccines.
    That is, about eight separate industries in different parts of the country, 50 million doses per year.
  14. lahudra Offline lahudra
    lahudra (Nikolay Kondrashkin) 30 November 2020 20: 25
    The largest Russian manufacturer Pharmsynthez from St. Petersburg will produce the AstraZeneca vaccine, not Sputnik.
  15. Natan bruk Offline Natan bruk
    Natan bruk (Nathan Brook) 3 December 2020 20: 11
    In the end, it seems, there will be the same zilch as with the Russian vaccine against Ebola. At one time it was very powerfully crowed that the Russian vaccine was the first and only one and it would save Africa and everyone else. As a result, it remained in the status of experimental, and the only one the American vaccine against Merck has become recognized and registered at the international level. But most of the local "patriots" do not know this, but remember that they were rubbed in by the "federal media".